2,6-dimethyl-4-(2-(4-fluorophenyl)ethenyl)phenol

Names

[ Name ]:
2,6-dimethyl-4-(2-(4-fluorophenyl)ethenyl)phenol

[Synonym ]:
2,6-Dimethyl-4-(2-(4-fluorophenyl)ethenyl)phenol

[Description]:

Enofelast (BI-L-239), a 5-lipoxygenase (5-LO) inhibitor, exhibits an IC50 of 2.48 μM for inhibition of calcium ionophore-induced LTB4 generation[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Leukotriene Receptor

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Metabolic Enzyme/Protease >> 5-Lipoxygenase

[Target]

IC50: 2.48 μM (LTB4)[1].

[References]

[ Molecular Formula ]:
C₁₆H₁₅FO

[ Molecular Weight ]:
242.28800

[ Exact Mass ]:
242.11100

[ PSA ]:
20.23000

[ LogP ]:
4.31850

[ Vapour Pressure ]:
1.79E-05mmHg at 25°C