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Icariside E4

Names

[ CAS No. ]:
126253-42-7

[ Name ]:
Icariside E4

Biological Activity

[Description]:

Icariside E4 is an antinociceptive agent, and can be isolated from Tabebuia roseo-alba. Icariside E4 has peripheral analgesic activity by ATP-sensitive K+ channel-dependent mechanisms. Icariside E4 also has anti-oxidant, anti-Alzheimer and anti-inflammatory effects[1][2].

[Related Catalog]:

Research Areas >> Inflammation/Immunology
Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel

[References]

[1]. Veiga TA, et al. Furoquinoline alkaloids isolated from Balfourodendron riedelianum as photosynthetic inhibitors in spinach chloroplasts. J Photochem Photobiol B. 2013 Mar 5;120:36-43.  

[2]. Suh JY, et al. Hypolipogenic effects of Icariside E4 via phosphorylation of AMPK and inhibition of MID1IP1 in HepG2 cells. Phytother Res. 2023 Jan;37(1):7-14.  

Chemical & Physical Properties

[ Density]:
1.348±0.06 g/cm3

[ Boiling Point ]:
693.3±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C26H34O10

[ Molecular Weight ]:
506.54

Related Compounds