sulfapyridine sodium

Names

[ CAS No. ]:
127-57-1

[ Name ]:
sulfapyridine sodium

[Synonym ]:
Sodium sulfapymonohydrate
Sulfanilsaeure-[2]pyridylamid,Natrium-Salz
Soluble sulfapyridine
EINECS 204-850-5
Sodium sulphapyridine
n1-2-pyridylsulfanilamide sodium salt
Sulfapyridine sodium salt monohydrate
Sulfapyridine,sodium salt
sodium salt of sulfanilic acid 2-pyridylamide
sulfanilic acid-[2]pyridylamide,sodium-salt
Sulfapyridine sodium
Sodium sulfapyridine
Soludagenan
Sulfanylsaeure-(2-pyridylamid)

Chemical & Physical Properties

[ Boiling Point ]:
473.5ºC at 760 mmHg

[ Molecular Formula ]:
C₁₁H₁₀N₃NaO₂S

[ Molecular Weight ]:
271.27100

[ Flash Point ]:
240.2ºC

[ Exact Mass ]:
271.03900

[ PSA ]:
81.43000

[ LogP ]:
3.71990

[ Vapour Pressure ]:
3.9E-09mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WD7175000

CHEMICAL NAME :: Sodium, (N(sup 1)-2-pyridylsulfanilamido)-

CAS REGISTRY NUMBER :: 127-57-1

LAST UPDATED :: 199701

DATA ITEMS CITED :: 12

MOLECULAR FORMULA :: C11-H10-N3-O2-S.Na

MOLECULAR WEIGHT :: 271.29

WISWESSER LINE NOTATION :: T6NJ BMSWR DZ &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2994 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JIDXA3 Journal of the Indiana State Medical Association. (Indiana State Medical Assoc., 3935 N. Meridian, Indianapolis, IN 46208) V.1- 1908- Volume(issue)/page/year: 33,503,1940

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1120 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 45,15,1940

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 648 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 33,80,1944

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 68,259,1940

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 910 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JIDXA3 Journal of the Indiana State Medical Association. (Indiana State Medical Assoc., 3935 N. Meridian, Indianapolis, IN 46208) V.1- 1908- Volume(issue)/page/year: 33,503,1940

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 872 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 71,138,1941

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 696 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JIDXA3 Journal of the Indiana State Medical Association. (Indiana State Medical Assoc., 3935 N. Meridian, Indianapolis, IN 46208) V.1- 1908- Volume(issue)/page/year: 33,503,1940

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1096 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JIDXA3 Journal of the Indiana State Medical Association. (Indiana State Medical Assoc., 3935 N. Meridian, Indianapolis, IN 46208) V.1- 1908- Volume(issue)/page/year: 33,503,1940

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 43,328,1940

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Primate - monkey

DOSE/DURATION :: 600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JIDXA3 Journal of the Indiana State Medical Association. (Indiana State Medical Assoc., 3935 N. Meridian, Indianapolis, IN 46208) V.1- 1908- Volume(issue)/page/year: 33,503,1940

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 693 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JIDXA3 Journal of the Indiana State Medical Association. (Indiana State Medical Assoc., 3935 N. Meridian, Indianapolis, IN 46208) V.1- 1908- Volume(issue)/page/year: 33,503,1940

Safety Information

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%