ODN 6016

Names

[ CAS No. ]:
1271731-64-6

[ Name ]:
ODN 6016

Biological Activity

[Description]:

ODN 6016 is a CpG-A oligonucleotides. ODN 6016 can induce IFN-α production, can be used for researching immune disorders including immunodeficiency caused by HIV-1. ODN 6016 sequence: T-sp-C-G-A-C-G-T-C-G-T-G-G-sp-G-sp-G-sp-G[1][2].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> IFNAR
Research Areas >> Inflammation/Immunology

[Target]

IFN-α[1]


[References]

[1]. Ries M, et al. Identification of novel oligonucleotides from mitochondrial DNA that spontaneously induce plasmacytoid dendritic cell activation. J Leukoc Biol. 2013 Jul;94(1):123-35.

[2]. Tennert K, et al. Elevated CD40 ligand silences α interferon production in an HIV-related immune reconstitution inflammatory syndrome. AIDS. 2013 Jan 14;27(2):297-9.

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds