<Suppliers Price>

Febuxostat impurity 6

Names

[ CAS No. ]:
1271738-74-9

[ Name ]:
Febuxostat impurity 6

[Synonym ]:
Ethyl 2-{3-[(E)-(hydroxyimino)methyl]-4-isobutoxyphenyl}-4-methyl-1,3-thiazole-5-carboxylate
5-Thiazolecarboxylic acid, 2-[3-[(E)-(hydroxyimino)methyl]-4-(2-methylpropoxy)phenyl]-4-methyl-, ethyl ester
2-[3-[(Hydroxyimino)methyl]-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic acid ethyl ester
Febuxostat Impurity 10

Biological Activity

[Description]:

Febuxostat impurity 6 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Leonid Metsger, et al. Processes for preparing febuxostat. WO2011031409A1.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
516.9±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C18H22N2O4S

[ Molecular Weight ]:
362.443

[ Flash Point ]:
266.4±32.9 °C

[ Exact Mass ]:
362.130035

[ LogP ]:
5.57

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.583

[ Water Solubility ]:
Insuluble (6.2E-3 g/L) (25 ºC)

Related Compounds