2-Ethyl-6-methylpyridin-3-ol succinate

Names

[ Name ]:
2-Ethyl-6-methylpyridin-3-ol succinate

[Synonym ]:
3-hydroxy-6-methyl-2-ethylpyridine succinate
3-Pyridinol, 2-ethyl-6-methyl-, butanedioate (1:1) (salt)
butanedioic acid,2-ethyl-6-methylpyridin-3-ol
Succinic acid - 2-ethyl-6-methyl-3-pyridinol (1:1)
Mexidol succinate

Biological Activity

[Description]:

Emoxypine succinate is an antioxidant. Emoxypine succinate can be used for the research of post-traumatic[1].

[Related Catalog]:

Research Areas >> Infection

Research Areas >> Inflammation/Immunology

[In Vitro]

Emoxypine succinate shows reactive oxygen species overproduction and disruption of the mitochondrial inner membrane due to the decreasing of transmembrane potential[1].

[In Vivo]

Emoxypine succinate (i.p.; 40 mg/kg; 1 time per day, 14 days) decreases the production of reactive oxygen species, mitochondrial transmembrane potential percentage of leukocyte and the percentage of FITC Annexin V- positive cells of leukocyte suspension[1]. Animal Model: Rats[1] Dosage: 40 mg/kg Administration: Intraperitoneal, 1 time per day, 14 days Result: Significantly increased the percentage of Annexin V-positive cells, reduced the apoptotic percentage of white blood cells and decreased the production of reactive oxygen species by leukocytes.

[References]

[1]. Krynytska, et al. Features of leukocytes’ apoptosis and emoxypine succinate efficacy in case of combined trauma of the chest and both thighs in rats. Bangladesh Journal of Medical Science, (2019). 18(2), 244-251.

Chemical & Physical Properties

[ Boiling Point ]:
280.6ºC at 760 mmHg

[ Melting Point ]:
113 °C

[ Molecular Formula ]:
C₁₂H₁₇NO₅

[ Molecular Weight ]:
255.267

[ Flash Point ]:
123.5ºC

[ Exact Mass ]:
255.110672

[ PSA ]:
107.72000

[ LogP ]:
1.59380

[ Vapour Pressure ]:
0.0022mmHg at 25°C

Safety Information

[ HS Code ]:
2933399090

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%