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Tr-PEG6-OH

Names

[ CAS No. ]:
127999-16-0

[ Name ]:
Tr-PEG6-OH

[Synonym ]:
2,5,8,11,14,17-Hexaoxanonadecan-19-ol, 1,1,1-triphenyl-
1,1,1-Triphenyl-2,5,8,11,14,17-hexaoxanonadecan-19-ol

Biological Activity

[Description]:

Tr-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Research Areas >> Inflammation/Immunology

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Subhadip Senapati, et al. A Y-Shaped Three-Arm Structure for Probing Bivalent Interactions between Protein Receptor–Ligand Using AFM and SPR. Langmuir. 2018 May.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
630.1±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C31H40O7

[ Molecular Weight ]:
524.645

[ Flash Point ]:
334.9±30.1 °C

[ Exact Mass ]:
524.277405

[ LogP ]:
3.62

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.543


Related Compounds