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Epipregnanolone

Names

[ CAS No. ]:
128-21-2

[ Name ]:
Epipregnanolone

[Synonym ]:
3.β.-Hydroxy-5.β.-tetrahydroprogesterone
3alpha-hydroxy-5beta-pregnan-20-one
5B-pregnan-3B-ol-20-one crystalline
3beta-hydroxy-5beta-pregnan-20-one

Biological Activity

[Description]:

Epipregnanolone is an endogenous neurosteroid that has anesthetic, hypnotic, and sedative properties.

[Related Catalog]:

Research Areas >> Others
Natural Products >> Others

[Target]

Human Endogenous Metabolite


[References]

[1]. Ayoola C, et al. Inhibition of CaV3.2 T-type calcium channels in peripheral sensory neurons contributes to analgesic properties of epipregnanolone. Psychopharmacology (Berl). 2014 Sep;231(17):3503-3515.


[Related Small Molecules]

3-Methyladenine | Hydrocortisone | Acetylcysteine(N-acetylcysteine) | Retinoic acid | Melatonine | Dinoprostone | Nicotinamide | Adenosine triphosphate | 4-Acetamidophenol | Prostaglandin E1 | Dehydroepiandrosterone | Corticosterone | Progesterone | Docosahexaenoic Acid | NAD+

Chemical & Physical Properties

[ Density]:
1.053 g/cm3

[ Boiling Point ]:
431.2ºC at 760 mmHg

[ Molecular Formula ]:
C21H34O2

[ Molecular Weight ]:
318.49300

[ Flash Point ]:
183.9ºC

[ Exact Mass ]:
318.25600

[ PSA ]:
37.30000

[ LogP ]:
4.59520

[ Vapour Pressure ]:
3.05E-09mmHg at 25°C

[ Index of Refraction ]:
1.524

Precursor & DownStream

Precursor

DownStream

Related Compounds