<Suppliers Price>

(+)-CBI-CDPI2

Names

[ CAS No. ]:
128300-15-2

[ Name ]:
(+)-CBI-CDPI2

[Synonym ]:
(+)-CBI-CDPI2
(+-)-Carvotanacetol-acetat
2-Cyclohexen-1-ol,2-methyl-5-(1-methylethyl)-,acetate

Biological Activity

[Description]:

(+)-CBI-CDPI2 is an enhanced functional analog of CC-1065. (+)-CBI-CDPI1 is a DNA alkylating agent. (+)-CBI-CDPI2 is an antibody drug conjugates (ADCs) toxin.

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Cytotoxin
Signaling Pathways >> Cell Cycle/DNA Damage >> DNA Alkylator/Crosslinker

[References]

[1]. Boger DL, et al. Molecular basis for sequence selective DNA alkylation by (+)- and ent-(-)-CC-1065 and related agents: alkylation site models that accommodate the offset AT-rich adenine N3 alkylation selectivity. Bioorg Med Chem. 1994 Feb;2(2):115-35.

Chemical & Physical Properties

[ Density]:
1.64g/cm3

[ Molecular Formula ]:
C36H28N6O4

[ Molecular Weight ]:
608.64500

[ Exact Mass ]:
608.21700

[ PSA ]:
136.59000

[ LogP ]:
5.36890

[ Index of Refraction ]:
1.88

Related Compounds