PyBOP

Names

[ Name ]:
PyBOP

[Synonym ]:
1H-Benzotriazol-1-yloxytripyrrolidinophosphonium Hexafluorophosphate
Benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate
PyBop
(1H-Benzotriazol-1-yloxy)(tri-1-pyrrolidinyl)phosphonium hexafluorophosphate
EINECS 260-279-1
(1H-Benzotriazol-1-yloxy)[tri(pyrrolidin-1-yl)]phosphonium hexafluorophosphate
(Benzotriazol-1-yloxy)tripyrrolidinophosphonium Hexafluorophosph
((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V)
(Benzotriazol-1-yloxy)tripyrrolidinophosphonium Hexafluorophosphate
Benzotriazol-1-yloxytripyrrolidinophosphonium hexafluorophosphate
MFCD00011948
(1H-Benzotriazol-1-yloxy)(tripyrrolidin-1-yl)phosphonium hexafluorophosphate
hexafluorophosphate de (1H-benzotriazol-1-yloxy)(tripyrrolidin-1-yl)phosphonium
benzotriazol-1-yloxy(tripyrrolidin-1-yl)phosphanium,hexafluorophosphate

Chemical & Physical Properties

[ Melting Point ]:
154-156 °C (dec.)(lit.)

[ Molecular Formula ]:
C₁₈H₂₈F₆N₆OP₂

[ Molecular Weight ]:
520.39200

[ Exact Mass ]:
520.17000

[ PSA ]:
76.84000

[ LogP ]:
6.02100

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
methanol: 25 mg/mL, clear

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S24/25

[ RIDADR ]:
UN 1325 4.1/PG 2

[ WGK Germany ]:
3

[ HS Code ]:
29339980

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Structural, nanomechanical, and computational characterization of D,L-cyclic peptide assemblies.

ACS Nano 9(3) , 3360-8, (2015)

The rigid geometry and tunable chemistry of D,L-cyclic peptides makes them an intriguing building-block for the rational design of nano- and microscale hierarchically structured materials. Herein, we ...

Parallel synthesis of cell-penetrating peptide conjugates of PMO toward exon skipping enhancement in Duchenne muscular dystrophy.

Nucleic Acid Ther. 25(1) , 1-10, (2015)

We describe two new methods of parallel chemical synthesis of libraries of peptide conjugates of phosphorodiamidate morpholino oligonucleotide (PMO) cargoes on a scale suitable for cell screening prio...

Bi-specific splice-switching PMO oligonucleotides conjugated via a single peptide active in a mouse model of Duchenne muscular dystrophy.

Nucleic Acids Res. 43(1) , 29-39, (2015)

The potential for therapeutic application of splice-switching oligonucleotides (SSOs) to modulate pre-mRNA splicing is increasingly evident in a number of diseases. However, the primary drawback of th...