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Tosylate of Hexaethylene glycol monobenzyl ether

Names

[ CAS No. ]:
129086-11-9

[ Name ]:
Tosylate of Hexaethylene glycol monobenzyl ether

[Synonym ]:
Toluene-4-sulfonic acid 2-[2-(2-{2-[2-(2-benzyloxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethyl ester

Biological Activity

[Description]:

Benzyl-PEG6-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs


[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Chemical & Physical Properties

[ Molecular Formula ]:
C26H38O9S

[ Molecular Weight ]:
526.64000

[ Exact Mass ]:
526.22400

[ PSA ]:
107.13000

[ LogP ]:
4.08090

Safety Information

[ Hazard Codes ]:
Xi


Related Compounds