PKI (14-24)amide TFA

Names

[ CAS No. ]:
1293946-39-0

[ Name ]:
PKI (14-24)amide TFA

Biological Activity

[Description]:

PKI (14-24)amide TFA is a potent PKA inhibitor. PKI (14-24)amide strongly inhibited cyclic AMP-dependent protein kinase activity in the cell homogenate[1][2].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> PKA
Signaling Pathways >> Stem Cell/Wnt >> PKA

[In Vitro]

PKI (14-24)amide TFA 不抑制环 AMP 诱发的皂素渗透细胞淀粉酶释放[2]。

[References]

[1]. Nörenberg W, et al. Adenosine A2A receptors inhibit the conductance of NMDA receptor channels in rat neostriatal neurons. Amino Acids. 1998;14(1-3):33-9.  

[2]. Takuma T. Evidence against direct involvement of cyclic AMP-dependent protein phosphorylation in the exocytosis of amylase. Biochem J. 1988 Dec 15;256(3):867-71.  

Chemical & Physical Properties

[ Molecular Formula ]:
C51H87F3N24O17

[ Molecular Weight ]:
1365.38

Related Compounds