5-Bromo-4-chloro-3-indolyl-N-acetyl-beta-D-galactosaminide

Names

[ Name ]:
5-Bromo-4-chloro-3-indolyl-N-acetyl-beta-D-galactosaminide

[Synonym ]:
5-bromo-4-chloro-3-indolyl-N-acetyl-B-D-galactosaminide
X-N-ACETYL-GALACTOSAMINIDE
X-Galactosaminide
5-Bromo-4-chloro-1H-indol-3-yl 2-acetamido-2-deoxy-β-D-glucopyranoside
X-GALNAC
N-Acetyl-5-bromo-4-chloro-3-indolyl-B-D-galactosaminide
MFCD00083260
β-D-Glucopyranoside, 5-bromo-4-chloro-1H-indol-3-yl 2-(acetylamino)-2-deoxy-

Biological Activity

[Description]:

X-GalNAc is a chromogenic substrate for for N-acetyl-β-galactosidase, used to determine the presence or absence of a cloned DNA insert in bacteria growing on agar plates[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Others >> Others

[References]

[1]. Smith WS, et al. Applying neutral drift to the directed molecular evolution of a β-glucuronidase into a β-galactosidase: Two different evolutionary pathways lead to the same variant. BMC Res Notes. 2011 May 6;4:138.

[2]. Semen A Leyn, et al. N-acetylgalactosamine utilization pathway and regulon in proteobacteria: genomic reconstruction and experimental characterization in Shewanella. J Biol Chem. 2012 Aug 10;287(33):28047-56.

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
777.5±60.0 °C at 760 mmHg

[ Melting Point ]:
220ºC(lit.)

[ Molecular Formula ]:
C₁₆H₁₈BrClN₂O₆

[ Molecular Weight ]:
449.681

[ Flash Point ]:
424.0±32.9 °C

[ Exact Mass ]:
448.003662

[ PSA ]:
124.04000

[ LogP ]:
1.39

[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C

[ Index of Refraction ]:
1.702

[ Storage condition ]:
−20°C

[ Water Solubility ]:
DMF: soluble

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3