L-Aspartic acid15N,2,3,3-d3

Names

[ Name ]:
L-Aspartic acid15N,2,3,3-d3

[Synonym ]:
MFCD04118130

Biological Activity

[Description]:

L-Aspartic acid-d3,15N is the deuterium and 15N-labeled L-Aspartic acid. L-Aspartic acid is an amino acid, shown to be a suitable prodrug for colon-specific drug deliverly.

[Related Catalog]:

Research Areas >> Cardiovascular Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

[ Melting Point ]:
>300 °C(dec.)(lit.)

[ Molecular Formula ]:
C₄H₄D₃₁₅NO₄

[ Molecular Weight ]:
137.11

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport