Propargyl-PEG4-Br

Names

[ CAS No. ]:
1308299-09-3

[ Name ]:
Propargyl-PEG4-Br

[Synonym ]:
1-Bromo-3,6,9,12-tetraoxapentadec-14-yne
3,6,9,12-Tetraoxapentadec-14-yne, 1-bromo-

[Description]:

Propargyl-PEG4-Br is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Non-cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
334.3±32.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₁H₁₉BrO₄

[ Molecular Weight ]:
295.170

[ Flash Point ]:
135.7±23.6 °C

[ Exact Mass ]:
294.046661

[ LogP ]:
0.37

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.476

[ Hazard Codes ]:
Xi