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HIV Protease Substrate VI

Names

[ CAS No. ]:
130877-92-8

[ Name ]:
HIV Protease Substrate VI

[Synonym ]:
L-Arginyl-L-valyl-L-norleucyl-4-nitro-L-phenylalanyl-L-α-glutamyl-L-alanyl-L-norleucinamide
L-Norleucinamide, L-arginyl-L-valyl-L-norleucyl-4-nitro-L-phenylalanyl-L-α-glutamyl-L-alanyl-
MFCD00237107

Biological Activity

[Description]:

Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2 is a fluorogenic substrate of HIV-1 protease. Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2 can be used to test HIV-1 protease activity[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Metabolic Enzyme/Protease >> HIV Protease

[References]

[1]. Schramm HJ, et, al. Lipopeptides as dimerization inhibitors of HIV-1 protease. Biol Chem. 1999 May;380(5):593-6.  

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C40H66N12O11

[ Molecular Weight ]:
891.03

[ Exact Mass ]:
890.497375

[ LogP ]:
0.82

[ Index of Refraction ]:
1.621

Related Compounds