MM 54
Names
[ CAS No. ]:
1313027-43-8
[ Name ]:
MM 54
Biological Activity
[Description]:
MM 54 is a potent apelin receptor antagonist (Ki=82 nM, IC50=93 nM). MM 54 antagonizes the inhibitory affect of [Pyr1]-Apelin-13 on forskolin-induced cAMP accumulation in CHO-K1-APJ cells. MM 54 recuces tumor expansion and lengthens survival time in a mouse xenograft model of glioblastoma.
[Related Catalog]:
Chemical & Physical Properties
[ Molecular Formula ]:
C70H121N29O15S4
[ Molecular Weight ]:
1737.17