ARRY-382

Names

[ Name ]:
ARRY-382

Biological Activity

[Description]:

c-Fms-IN-12 is a c-Fms inhibitor extracted from patent WO2011079076A1, Compound Example 65, has an IC50 of 93.6-283.7 nM[1].

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> c-Fms

[Target]

c-Fms[1]

[In Vitro]

cFMS, a type III receptor tyrosine kinases, which are useful in the treatment of bone-related diseases, cancer, autoimmune disorders, inflammatory diseases, cardiovascular diseases and pain[1].

[References]

[1]. Mark Laurence Boys, et al. Substituted n-(1h-indazol-4-yl)imidazo[1, 2-a]pyridine-3- carboxamide compounds as cfms inhibitors. WO2011079076A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₂H₃₆N₈O₂

[ Molecular Weight ]:
564.68

ARRY-382

Names

Biological Activity

Chemical & Physical Properties

Related Compounds