Neuropeptide Y (1-24) amide (human, rat) trifluoroacetate salt

Names

[ Name ]:
Neuropeptide Y (1-24) amide (human, rat) trifluoroacetate salt

[Synonym ]:
NEUROPEPTIDE Y FRAGMENT 1-24 AMIDE HUMAN
npy 1-24
Neuropeptide Y Fragment 1-24 Amide human
TYR-PRO-SER-LYS-PRO-ASP-ASN-PRO-GLY-GLU-ASP-ALA-PRO-ALA-GLU-ASP-MET-ALA-ARG-TYR-TYR-SER-ALA-LEU-NH2
neuropeptide Y,fragment 1-24 amide
YPSKPDNPGEDAPAEDMARYYSAL-NH2

Biological Activity

[Description]:

Neuropeptide Y (1-24) (human) is a neuropeptide with potencies in inhibiting the electricity stimulated twitch response of rat vas deferens. Neuropeptide Y (1-24) (human) stimulates N-methyl-D-aspartate (NMDA)-induced neuronal activation in the rat CA3 region of the dorsal hippocampus in vivo[1][2].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Neuropeptide Y Receptor

[In Vitro]

Neuropeptide Y (1-24) (human) dose-dependently enhances N-methyl-D-aspartate (NMDA)-induced activation of CA3 dorsal hippocampus pyramidal neurons[1]. Neuropeptide Y (1-24) (human) selectively increases the amplitude of the twitch response to electrical stimulation at low micromolar concentrations but shows no affinity toward [3H]NPY brain receptor sites and no inhibition of the twitch response in the rat vas deferens preparation at concentrations up to 1.0 mM[2].

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₁₆H₁₇₀N₃₀O₄₀S

[ Molecular Weight ]:
2656.83000

[ Exact Mass ]:
2655.19000

[ PSA ]:
1147.21000

Safety Information

[ WGK Germany ]:
3