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CefepiMe-D8 Sulfate

Names

[ CAS No. ]:
131857-33-5

[ Name ]:
CefepiMe-D8 Sulfate

[Synonym ]:
(6R,7R)-7-{[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[1-methyl(2H8)-1-pyrrolidiniumyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate sulfate (1:1)

Biological Activity

[Description]:

Cefepime-d8 (sulfate) is the deuterium labeled Cefepime sulfate[1].

[Related Catalog]:

Research Areas >> Others

[In Vitro]

氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-238.  

Chemical & Physical Properties

[ Molecular Formula ]:
C19H18D8N6O9S3

[ Molecular Weight ]:
586.689

[ Exact Mass ]:
586.142578

Related Compounds