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Cipamfylline

Names

[ CAS No. ]:
132210-43-6

[ Name ]:
Cipamfylline

[Synonym ]:
Cipamfylline
8-Amino-1,3-bis(cyclopropylmethyl)-3,9-dihydro-1H-Purine-2,6-dione BRL 61063
Cipamfyllinum

Chemical & Physical Properties

[ Density]:
1.538g/cm3

[ Boiling Point ]:
555.2ºC at 760mmHg

[ Molecular Formula ]:
C13H17N5O2

[ Molecular Weight ]:
275.30600

[ Flash Point ]:
289.6ºC

[ Exact Mass ]:
275.13800

[ PSA ]:
98.70000

[ LogP ]:
0.86970

[ Vapour Pressure ]:
2.3E-12mmHg at 25°C

[ Index of Refraction ]:
1.724

MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

Beneficial effects of the phosphodiesterase inhibitors BRL 61063, pentoxifylline, and rolipram in a murine model of endotoxin shock.

Circ. Shock. 44(4) , 188-95, (1994)

Three inhibitors of calcium-dependent cyclic adenosine 3'5'-monophosphate (cAMP) dependent phosphodiesterase IV (PDE IV) were evaluated for their effects on lipopolysaccharide (LPS)-induced tumor necr...

Stimulation of the hypothalamo-pituitary-adrenal axis in the rat by three selective type-4 phosphodiesterase inhibitors: in vitro and in vivo studies.

Br. J. Pharmacol. 121(3) , 459-68, (1997)

1. Previous studies in our laboratory have shown that the synthetic xanthine analogue denbufylline, a selective type 4 phosphodiesterase (PDE-4) inhibitor, is a potent activator of the hypothalamo-pit...

Identification, characterization, and functional role of phosphodiesterase type IV in cerebral vessels: effects of selective phosphodiesterase inhibitors.

J. Cereb. Blood Flow Metab. 17(2) , 210-9, (1997)

The role of the phosphodiesterase type IV isozyme (PDE IV) in the regulation of cerebrovascular tone was investigated in the canine basilar artery in vitro and in vivo. The PDE isozymes extracted from...


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