Ethylenediaminetetraacetic acid tetrasodium salt

Names

[ Name ]:
Ethylenediaminetetraacetic acid tetrasodium salt

[Synonym ]:
Ethylenediaminetetraacetic Acid Tetrasodium Salt Tetrahydrate
Ethylenediaminetetraacetic acid tetrasodium salt
MFCD00150027
EINECS 200-573-9
tetrasodium,2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate,tetrahydrate
TetrasodiuM EthylenediaMinetetraacetate Tetrahydrate
Sodium 2,2',2'',2'''-(1,2-ethanediyldinitrilo)tetraacetate hydrate (4:1:4)

Biological Activity

[Description]:

EDTA tetrasodium tetrahydrate is a metal chelator (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. EDTA tetrasodium tetrahydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. EDTA tetrasodium tetrahydrate can also decrease the formation of disulfide bonds[1][2][3].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Chumanov RS, et al. Artifact-inducing enrichment of ethylenediaminetetraacetic acid and ethyleneglycoltetraacetic acid on anion exchange resins. Anal Biochem. 2011 May 1;412(1):34-9.

[2]. Banfi G, et al. The role of ethylenediamine tetraacetic acid (EDTA) as in vitro anticoagulant for diagnostic purposes. Clin Chem Lab Med. 2007;45(5):565-76.

[3]. Ibad A, et al. Chelation therapy in the treatment of cardiovascular diseases. J Clin Lipidol. 2016 Jan-Feb;10(1):58-62.

Chemical & Physical Properties

[ Boiling Point ]:
614.2ºCat 760 mmHg

[ Molecular Formula ]:
C₁₀H₂₀N₂Na₄O₁₂

[ Molecular Weight ]:
452.231

[ Flash Point ]:
325.2ºC

[ Exact Mass ]:
452.060699

[ PSA ]:
203.92000

[ Water Solubility ]:
H2O: 0.1 M at 20 °C, clear, colorless

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
UN 2910 7

[ WGK Germany ]:
3

[ RTECS ]:
AH5075000

[ HS Code ]:
2922499990

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%