Mexiletine D6 hydrochloride

Names

[ Name ]:
Mexiletine D6 hydrochloride

[Synonym ]:
2-Propan-1,1,2,3,3,3-d6-amine, 1-(2,6-dimethylphenoxy)-, hydrochloride (1:1)
1-(2,6-Dimethylphenoxy)-2-(2H6)propanamine hydrochloride (1:1)

Biological Activity

[Description]:

Mexiletine D6 hydrochloride (KOE-1173 D6 hydrochloride) is a deuterium labeled Mexiletine hydrochloride (KOE-1173 hydrochloride). Mexiletine hydrochloride, a Class IB antianhythmic, is a non-selective voltage-gated sodium channel blocker[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel

Research Areas >> Cardiovascular Disease

[References]

[1]. Mori K, et al. Inhibitory effects of class I and IV antiarrhythmic drugs on the Na+-activated K+ channel current in guinea pig ventricular cells. Naunyn Schmiedebergs Arch Pharmacol. 1998 Dec;358(6):641-8.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₁H₁₂D₆ClNO

[ Molecular Weight ]:
221.757

[ Exact Mass ]:
221.145355

Mexiletine D6 hydrochloride

Names

Biological Activity

Chemical & Physical Properties

Related Compounds