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Ramifenazone-d7

Names

[ CAS No. ]:
1330180-51-2

[ Name ]:
Ramifenazone-d7

Biological Activity

[Description]:

Ramifenazone-d7 (Isopropylaminoantipyrine-d7) is the deuterium labeled Ramifenazone. Ramifenazone (Isopropylaminoantipyrine) is a pyrazole derivative and acts as a non-steroidal anti-inflammatory agent (NSAID). Ramifenazone has analgesic, antipyretic, anti-inflammatory and antimicrobial activities[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Bhupender Nehra, et al. Recent advancements in the development of bioactive pyrazoline derivatives. Eur J Med Chem. 2020 Nov 1;205:112666.

[3]. R Surendra Kumar, et al. Anti-inflammatory and antimicrobial activities of novel pyrazole analogues. Saudi J Biol Sci. 2016 Sep;23(5):614-20.

Chemical & Physical Properties

[ Molecular Formula ]:
C14H12D7N3O

[ Molecular Weight ]:
252.36

Related Compounds