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4-O-Methylbutein

Names

[ CAS No. ]:
13323-67-6

[ Name ]:
4-O-Methylbutein

[Synonym ]:
(2E)-1-(2,4-Dihydroxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)-2-propen-1-one
2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)-, (2E)-
4-O-Methylbutein
Acrylophenone,2',4'-dihydroxy-3-(m-hydroxy-p-methoxyphenyl)
Chalcone, 2',3,4'-trihydroxy-4-methoxy-
2-PROPEN-1-ONE,1-(2,4-DIHYDROXYPHENYL)-3-(3-HYDROXY-4-METHOXYPHENYL)
Chalcone,2',3,4'-trihydroxy-4-methoxy
1-(2,4-Dihydroxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)-2-propen-1-one
3,2',4'-Trihydroxy-4-methoxychalcone
2',3,4'-Trihydroxy-4-methoxy-chalcon

Biological Activity

[Description]:

4-O-Methylbutein is a phenolic glucoside that can be isolated from Elsholtzia ciliata.4-O-Methylbutein exhibits neuroprotective effects against glutamate-induced HT22 cell death with an EC50 of 35.2 μM[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[References]

[1]. Seo YH, et al. Chemical Constituents from the Aerial Parts of Elsholtzia ciliata and Their Protective Activities on Glutamate-Induced HT22 Cell Death. J Nat Prod. 2020 Oct 23;83(10):3149-3155.  

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
555.6±50.0 °C at 760 mmHg

[ Melting Point ]:
198.5-200.5℃

[ Molecular Formula ]:
C16H14O5

[ Molecular Weight ]:
286.28

[ Flash Point ]:
210.6±23.6 °C

[ Exact Mass ]:
286.084137

[ PSA ]:
86.99000

[ LogP ]:
2.80

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.684

[ Storage condition ]:
2-8℃

Safety Information

[ Hazard Codes ]:
Xn

Precursor & DownStream

Precursor

DownStream

Related Compounds