Hydroxy-PEG8-Boc

Names

[ Name ]:
Hydroxy-PEG8-Boc

[Synonym ]:
2-Methyl-2-propanyl 1-hydroxy-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate
3,6,9,12,15,18,21,24-Octaoxaheptacosan-27-oic acid, 1-hydroxy-, 1,1-dimethylethyl ester

Biological Activity

[Description]:

Hydroxy-PEG8-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
549.5±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₃H₄₆O₁₁

[ Molecular Weight ]:
498.605

[ Flash Point ]:
168.6±22.2 °C

[ Exact Mass ]:
498.304016

[ LogP ]:
-1.81

[ Vapour Pressure ]:
0.0±3.4 mmHg at 25°C

[ Index of Refraction ]:
1.459

[ Storage condition ]:
2-8°C

Hydroxy-PEG8-Boc

Names

Biological Activity

Chemical & Physical Properties

Related Compounds