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PBK-IN-9

Names

[ CAS No. ]:
1338540-55-8

[ Name ]:
PBK-IN-9

[Synonym ]:
9-{4-[(2R)-1-Amino-2-propanyl]phenyl}-8-hydroxythieno[2,3-c]quinolin-4(5H)-one
Thieno[2,3-c]quinolin-4(5H)-one, 9-[4-[(1R)-2-amino-1-methylethyl]phenyl]-8-hydroxy-

Biological Activity

[Description]:

PBK-IN-9 (compound 1160) is a potent PDZ binding kinase (PBK) inhibitor[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> TOPK

[References]

[1]. Yusuke Nakamura, et al. Trycyclic compounds and pbk inhibitors containing the same. WO2011123419A1.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
498.7±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H18N2O2S

[ Molecular Weight ]:
350.434

[ Flash Point ]:
255.4±28.7 °C

[ Exact Mass ]:
350.108887

[ LogP ]:
2.79

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.676

Related Compounds