WWL229

Names

[ Name ]:
WWL229

[Synonym ]:
4-Nitrophenyl 2-(3-methoxypropyl)-1-piperidinecarboxylate
4-Nitrophenyl 2-(3-methoxypropyl)piperidine-1-carboxylate
1-Piperidinecarboxylic acid, 2-(3-methoxypropyl)-, 4-nitrophenyl ester

Biological Activity

[Description]:

WWL229 is a selective inhibitor of carboxylesterase 3 (Ces3) with an IC50 of 1.94 µM. WWL229 promotes lipid storage in cultured adipocytes and prevents basal lipolysis[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Dominguez E, et al. Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes. Nat Chem Biol. 2014 Feb;10(2):113-21.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
449.1±41.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₆H₂₂N₂O₅

[ Molecular Weight ]:
322.356

[ Flash Point ]:
225.4±27.6 °C

[ Exact Mass ]:
322.152863

[ PSA ]:
84.59000

[ LogP ]:
3.56

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.538

Safety Information

[ RIDADR ]:
NONH for all modes of transport