PDE10A-IN-32

Names

[ Name ]:
PDE10A-IN-32

Biological Activity

[Description]:

PDE10A-IN-32 is a potent, highly selective, brain penetrant PDE10A inhibitor with IC50 of 0.14 nM, displays no significant activity against other PDEs (IC50>1,000 nM).

[References]

References 1. Kadoh Y, et al. Chem Pharm Bull (Tokyo). 2018;66(3):243-250. View Related Products by Target Phosphodiesterase (PDE)

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₂₈ClFN₆O

[ Molecular Weight ]:
470.977

Related Compounds

PDE10A-IN-31
EGFR-IN-32
ROMK-IN-32
LSD1-IN-32
ALK5-IN-32
HPK1-IN-32
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
2-Bromo-5-difluoromethoxy-4-nitrotoluene
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
2-methyl-2-(1-methyl-1H-indol-5-yl)propan-1-ol
tert-Butyl-DL-alanine