<Suppliers Price>

Fluorodeoxyuridylate

Names

[ CAS No. ]:
134-46-3

[ Name ]:
Fluorodeoxyuridylate

[Synonym ]:
5-F-dUMP
FdUMP
5-fluoro-2'-deoxyuridine monophosphate
5-fluoro-2'-deoxyuridine-5'-O-monophosphate
5-fluoro-2'-deoxyuridine-5'-monophosphate
5-fluoro-2'-deoxyuridine 5'-monophosphate

Biological Activity

[Description]:

2’-Deoxy-5-Fluorouridine 5’-phosphate (triethylammonium) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C21H42FN4O8P

[ Molecular Weight ]:
528.55

[ Exact Mass ]:
326.03200

[ PSA ]:
160.89000

Related Compounds