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MC-Val-Ala-OH

Names

[ CAS No. ]:
1342211-31-7

[ Name ]:
MC-Val-Ala-OH

[Synonym ]:
MFCD27956998

Biological Activity

[Description]:

MC-Val-Ala-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[References]

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Chemical & Physical Properties

[ Density]:
1.232±0.06 g/cm3(Predicted)

[ Boiling Point ]:
695.4±50.0 °C(Predicted)

[ Molecular Formula ]:
C18H27N3O6

[ Molecular Weight ]:
381.42

Safety Information

[ Hazard Codes ]:
Xn


Related Compounds