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Propafenone-d5 (hydrochloride)

Names

[ CAS No. ]:
1346605-05-7

[ Name ]:
Propafenone-d5 (hydrochloride)

[Synonym ]:
1-Propanone, 1-[2-[[2-hydroxy-3-(propylamino)propyl-1,1,2,3,3-d5]oxy]phenyl]-3-phenyl-, hydrochloride (1:1)
1-(2-{[2-Hydroxy-3-(propylamino)(2H5)propyl]oxy}phenyl)-3-phenyl-1-propanone hydrochloride (1:1)

Biological Activity

[Description]:

Propafenone D5 (SA-79 D5) hydrochloride is the deuterium labeled Propafenone hydrochloride. Propafenone (SA-79) hydrochloride is a class of anti-arrhythmic medication, which treats illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel
Research Areas >> Cardiovascular Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Cox L, et al. Levomepromazine for nausea and vomiting in palliative care. Cochrane Database Syst Rev. 2015;2015(11):CD009420. Published 2015 Nov 2.

[2]. http://en.wikipedia.org/wiki/Propafenone

Chemical & Physical Properties

[ Molecular Formula ]:
C21H23D5ClNO3

[ Molecular Weight ]:
382.936

[ Exact Mass ]:
382.207153


Related Compounds