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A 412997 dihydrochloride

Names

[ CAS No. ]:
1347744-96-0

[ Name ]:
A 412997 dihydrochloride

[Synonym ]:
1-Piperidineacetamide, N-(3-methylphenyl)-4-(2-pyridinyl)-, hydrochloride (1:2)
MFCD22373818
N-(3-Methylphenyl)-2-[4-(2-pyridinyl)-1-piperidinyl]acetamide dihydrochloride

Biological Activity

[Description]:

A-412997 dihydrochloride is a selective dopamine D4 receptor agonist. A-412997 dihydrochloride improves cognitive performance in rats and can be used in the research of psychiatric diseases[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor
Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor
Research Areas >> Neurological Disease

[References]

[1]. Browman KE, et al. A-412997, a selective dopamine D4 agonist, improves cognitive performance in rats. Pharmacol Biochem Behav. 2005 Sep;82(1):148-55.  

Chemical & Physical Properties

[ Molecular Formula ]:
C19H25Cl2N3O

[ Molecular Weight ]:
382.33

[ Exact Mass ]:
381.137482

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H315-H319-H335

[ Precautionary Statements ]:
P261-P301 + P310-P305 + P351 + P338

[ RIDADR ]:
UN 2811 6.1 / PGIII

Related Compounds