Propargyl-PEG4-thiol

Names

[ CAS No. ]:
1347750-80-4

[ Name ]:
Propargyl-PEG4-thiol

[Synonym ]:
3,6,9,12-Tetraoxapentadec-14-yne-1-thiol

[Description]:

Propargyl-PEG4-thiol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Non-cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
332.9±37.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₁H₂₀O₄S

[ Molecular Weight ]:
248.339

[ Flash Point ]:
155.1±26.5 °C

[ Exact Mass ]:
248.108231

[ LogP ]:
0.09

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.475

[ Hazard Codes ]:
Xi