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PROTAC AR Degrader-4

Names

[ CAS No. ]:
1351169-31-7

[ Name ]:
PROTAC AR Degrader-4

Biological Activity

[Description]:

PROTAC AR Degrader-4 comprises a cIAP1 ligand binding group, a linker and an androgen receptor (AR) binding group. PROTAC AR Degrader-4 is an AR degrader. Degradation inducers based on cIAP1 are called specific and non-genetic IAP-dependent protein erasers (SNIPERs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC
Signaling Pathways >> Others >> Androgen Receptor

[References]

[1]. Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19(22):6768-78.

Chemical & Physical Properties

[ Molecular Formula ]:
C43H67N3O9

[ Molecular Weight ]:
770.01

[ Storage condition ]:
2-8°C


Related Compounds