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T338C Src-IN-1

Names

[ CAS No. ]:
1351926-90-3

[ Name ]:
T338C Src-IN-1

[Synonym ]:
T338C Src-IN-1

Biological Activity

[Description]:

T338C Src-IN-1 is a potent mutant-Src T338C inhibitor; exhibited the most potent inhibition of T338C(IC50=111 nM) relative to WT c-Src (10-fold increase).

[Related Catalog]:

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Src
Research Areas >> Cancer

[References]

[1]. Garske AL, et al. Chemical genetic strategy for targeting protein kinases based on covalent complementarity. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15046-52.


[Related Small Molecules]

Saracatinib | PP2 (AG 1879) | A 419259 trihydrochloride | DCC-2036 (Rebastinib) | SU6656 | 1-Naphthyl PP1 | WH-4-023 | Pelitinib | Src Inhibitor-1 | ENMD-2076 | TC-S 7003 | PD173955 | TG 100572 (Hydrochloride) | XL228 | A-196

Chemical & Physical Properties

[ Molecular Formula ]:
C17H20N6O2S

[ Molecular Weight ]:
372.44500

[ Exact Mass ]:
372.13700

[ PSA ]:
124.17000

[ LogP ]:
4.20040

[ Storage condition ]:
2-8℃

Related Compounds