trijuganone C

Names

[ Name ]:
trijuganone C

[Synonym ]:
Phenanthro(1,2-b)furan-6-carboxylic acid,1,2,6,7,8,9,10,11-octahydro-1,6-dimethyl-10,11-dioxo-,methyl ester
Trijuganone C

Biological Activity

[Description]:

Trijuganone C, a natural product extracted from Salvia miltiorrhiza, inhibits the proliferation of cancer cells through induction of apoptosis mediated by mitochondrial dysfunction and caspase activation[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Apoptosis >> Caspase

[Target]

caspase

[References]

[1]. Uto T, et al. Antiproliferative activity and apoptosis induction by trijuganone C isolated from the root of Salvia miltiorrhiza Bunge (Danshen). Phytother Res. 2018 Apr;32(4):657-666.

Chemical & Physical Properties

[ Density]:
1.31g/cm3

[ Boiling Point ]:
502.1ºC at 760mmHg

[ Molecular Formula ]:
C₂₀H₂₀O₅

[ Molecular Weight ]:
340.37

[ Flash Point ]:
221.5ºC

[ Exact Mass ]:
340.13100

[ PSA ]:
69.67000

[ LogP ]:
2.59640

[ Vapour Pressure ]:
3.29E-10mmHg at 25°C

[ Index of Refraction ]:
1.601

trijuganone C

Names

Biological Activity

Chemical & Physical Properties

Related Compounds