BChE-IN-12

Names

[ CAS No. ]:
136966-86-4

[ Name ]:
BChE-IN-12

Biological Activity

[Description]:

BChE-IN-12 (compound 12) is a potent butyrylcholinesterase (BChE) non-competitive inhibitor with an IC50 value of 2.3 μM. BChE-IN-12 can be isolated from Bletilla striata. BChE-IN-12 can be used for the research of Alzheimer's disease (AD)[1].

[Related Catalog]:

Research Areas >> Neurological Disease
Signaling Pathways >> Neuronal Signaling >> AChE

[Target]

BChE:2.3 μM (IC50)


[References]

[1]. Liu Y, et al. Biological evaluation, molecular modeling and dynamics simulation of phenanthrenes isolated from Bletilla striata as butyrylcholinesterase inhibitors. Sci Rep. 2022 Aug 11;12(1):13649.

Chemical & Physical Properties

[ Molecular Formula ]:
C31H30O5

[ Molecular Weight ]:
482.57

Related Compounds