PACAP(6-38), human, ovine, rat
Names
[ CAS No. ]:
137061-48-4
[ Name ]:
PACAP(6-38), human, ovine, rat
Biological Activity
[Description]:
[Related Catalog]:
[Target]
IC50: 4 nM (PACAP type I receptor), 2 nM (PACAP type II receptor VIP1), and 1 nM (PACAP type II receptor VIP2)[1]
[In Vitro]
[In Vivo]
[Animal admin]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Molecular Formula ]:
C203H331N63O53S
[ Molecular Weight ]:
4534.26
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
Articles
BMB Rep. 49 , 128-33, (2016)
Astrocytes play a critical role in normal brain functions and maintaining the brain microenvironment, and defects in astrocytogenesis during neurodevelopment could give rise to severe mental illness a...
The role of VIP/PACAP receptor subtypes in spinal somatosensory processing in rats with an experimental peripheral mononeuropathy.Neuropharmacology 38 , 167-180, (1999)
Peripheral nerve damage often results in the development of chronic pain states, resistant to classical analgesics. Since vasoactive intestinal polypeptide (VIP) and pituitary adenylate cyclase-activa...
Pituitary adenylate cyclase-activating peptide 38 a potent endogenously produced dilator of human airways.Eur. Respir. J. 15 , 243-247, (2000)
Pituitary adenylate cyclase-activating peptide (PACAP) 38 displays several biological activities relevant to obstructive airway disease. In this study, the occurrence of PACAP 38 in human small bronch...