L-Leucic acid

Names

[ Name ]:
L-Leucic acid

[Synonym ]:
(S)-2-hydroxy-4-methyl-Pentanoic acid
L-Leucic Acid
(S)-2-Hydroxy-4-methylvaleric Acid
S-2-Hydroxy-4-methylpentanoic acid
(S)-leucic acid
(S)-2-Hydroxy-4-methylpentanoic acid
EINECS 237-329-6
(+)-2-hydroxyisocaproic acid
(S)-(？)-2-Hydroxyisocaproic acid
(2S)-2-hydroxy-4-methyl-pentanoic acid
Pentanoic acid, 2-hydroxy-4-methyl-, (2S)-
L-alpha-Hydroxyisocaproic acid
MFCD00064214
(2S)-2-Hydroxy-4-methylpentanoic acid
(+)-α-Hydroxyisocaproic acid

Biological Activity

[Description]:

(S)-Leucic acid is an amino acid metabolite.

[Related Catalog]:

Natural Products >> Others

Research Areas >> Others

[Target]

Human Endogenous Metabolite

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
251.3±13.0 °C at 760 mmHg

[ Melting Point ]:
78-80ºC(lit.)

[ Molecular Formula ]:
C₆H₁₂O₃

[ Molecular Weight ]:
132.158

[ Flash Point ]:
120.1±16.3 °C

[ Exact Mass ]:
132.078644

[ PSA ]:
57.53000

[ LogP ]:
0.71

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.458

[ Storage condition ]:
-15°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2918199090

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918199090

[ Summary ]:
2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Renal clearance of branched-chain L-amino and 2-oxo acids in maple syrup urine disease.

J. Inherit. Metab. Dis. 22(6) , 706-22, (1999)

In maple syrup urine disease (MSUD), branched-chain L-amino (BCAA) and 2-oxo acids (BCOA) accumulate in body fluids owing to an inherited deficiency of branched-chain 2-oxo acid dehydrogenase complex ...

Rapid diagnosis of phenylketonuria and other aminoacidemias by quantitative analysis of amino acids in neonatal blood spots by gas chromatography-mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 775(1) , 115-20, (2002)

A new method for quantifying specific amino acids in small volumes of plasma and whole blood has been developed. Volatile derivatives of amino acids are analyzed by gas chromatography-mass spectrometr...

Hydroxy acid metabolites of branched-chain amino acids in amniotic fluid.

Clin. Chim. Acta 140(2) , 157-66, (1984)

A method is described in which ammonia chemical ionization gas chromatography-mass spectrometry was utilized in the selected ion monitoring mode to provide an accurate, selective approach to the quant...