2,3-Bis(3-indolylmethyl)indole

Names

[ Name ]:
2,3-Bis(3-indolylmethyl)indole

[Synonym ]:
1H-Indole,2,3-bis(1H-indol-3-ylmethyl)
2-(indol-3-ylmethyl)-3,3'-diindolylmethane
Bisimi
2,3-diskatylindole
3,3'-indole-2,3-diyldimethyl-bis-indole
2-(indol-3-ylmethyl)-3,3'-methylenediindole
2,3-Bis(3-indolylmethyl)indole
3,3'-(1H-indole-2,3-diyl)bis(methylene)bis(1H-indole)

Biological Activity

[Description]:

2,3-Bis(3-indolylmethyl)indole significantly suppresses RANKL-induced osteoclast formation, actin ring formation, and bone resorption in a concentration-dependent manner.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Ha MT, et al. Anti-osteoclastogenic Effects of Indole Alkaloids Isolated from Barley (Hordeum vulgare Var. Hexastichon) Grass. J Agric Food Chem. 2021 Nov 10;69(44):12994-13005.

Chemical & Physical Properties

[ Density]:
1.314g/cm3

[ Boiling Point ]:
682.1ºC at 760mmHg

[ Molecular Formula ]:
C₂₆H₂₁N₃

[ Molecular Weight ]:
375.47

[ Flash Point ]:
306.6ºC

[ Exact Mass ]:
375.17400

[ PSA ]:
47.37000

[ LogP ]:
6.31210

[ Vapour Pressure ]:
1.09E-17mmHg at 25°C

[ Index of Refraction ]:
1.796

2,3-Bis(3-indolylmethyl)indole

Names

Biological Activity

Chemical & Physical Properties

Precursor & DownStream

Precursor

DownStream

Related Compounds