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PACAP-38 (31-38) (human, chicken, mouse, ovine, porcine, rat) trifluoroacetate salt

Names

[ CAS No. ]:
138764-85-9

[ Name ]:
PACAP-38 (31-38) (human, chicken, mouse, ovine, porcine, rat) trifluoroacetate salt

[Synonym ]:
tyr-lys-gln-arg-val-lys-asn-lys-nh2
pacap 1-38
pituitary adenylate cyclase-activating polypeptide 1-38
h-tyr-lys-gln-arg-val-lys-asn-lys-nh2

Biological Activity

[Description]:

PACAP-38 (31-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production[1]. PACAP is a potent activator of cAMP formation[2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

[References]

[1]. Braas KM, et al. Pituitary adenylate cyclase-activating polypeptides, PACAP-38 and PACAP-27, regulation of sympathetic neuron catecholamine, and neuropeptide Y expression through activation of type I PACAP/VIP receptor isoforms. Ann N Y Acad Sci. 1996 Dec 26;805:204-16.

[2]. Lania A, et al. Mechanism of action of pituitary adenylate cyclase-activating polypeptide (PACAP) in human nonfunctioning pituitary tumors. J Neuroendocrinol. 1995 Sep;7(9):695-702.

Chemical & Physical Properties

[ Molecular Formula ]:
C47H83N17O11

[ Molecular Weight ]:
1062.27

[ Exact Mass ]:
1061.65000

[ PSA ]:
519.18000

[ LogP ]:
3.41740

[ Storage condition ]:
-20°C

Related Compounds