Tripterifordin

Names

[ Name ]:
Tripterifordin

[Synonym ]:
(8α,10α,13α,16β)-16-Hydroxy-18,20-epoxykauran-18-one
(5β,8α,10α,13α,16β)-16-Hydroxy-18,20-epoxykauran-18-one
Tripterifordin

Biological Activity

[Description]:

Tripterifordin, isolated from the roots of Tripterygium wilfordii, possesses significant anti-HIV replication activities in H9 lymphocyte cells with an EC50 value of 3100 nM, respectively[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HIV

Research Areas >> Infection

[References]

[1]. Kobayashi S, et al. Syntheses of (-)-Tripterifordin and (-)-Neotripterifordin from Stevioside.J Org Chem. 2018 Feb 2;83(3):1606-1613.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
485.1±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₃₀O₃

[ Molecular Weight ]:
318.450

[ Flash Point ]:
198.6±21.5 °C

[ Exact Mass ]:
318.219482

[ PSA ]:
46.53000

[ LogP ]:
3.20

[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C

[ Index of Refraction ]:
1.570

Safety Information

[ Hazard Codes ]:
Xi