Lexipafant

Names

[ Name ]:
Lexipafant

Biological Activity

[Description]:

Lexipafant is a platelet-activating factor (PAF) antagonist that inhibits the inflammatory response and is used in the treatment of acute pancreatitis.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Kingsnorth AN, Galloway SW, Formela LJ. Randomized, double-blind phase II trial of Lexipafant, a platelet-activating factor antagonist, in human acute pancreatitis. Br J Surg. 1995;82(10):1414-1420.

[2]. Galloway SW, Kingsnorth AN. Lung injury in the microembolic model of acute pancreatitis and amelioration by lexipafant (BB-882), a platelet-activating factor antagonist. Pancreas. 1996;13(2):140-146.

Chemical & Physical Properties

[ Density]:
1.24g/cm3

[ Boiling Point ]:
639.3ºC at 760 mmHg

[ Molecular Formula ]:
C₂₃H₃₀N₄O₄S

[ Molecular Weight ]:
458.57400

[ Flash Point ]:
340.5ºC

[ Exact Mass ]:
458.19900

[ PSA ]:
102.77000

[ LogP ]:
4.46710

[ Vapour Pressure ]:
3.05E-16mmHg at 25°C

[ Index of Refraction ]:
1.601