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Fusafungine

Names

[ CAS No. ]:
1393-87-9

[ Name ]:
Fusafungine

[Synonym ]:
Enniatin B
EINECS 215-737-5
1,7,13-Trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone, 4,10,16-trimethyl-3,6,9,12,15,18-hexakis(1-methylethyl)-, (3S,6R,9S,12R,15S,18R)-
(-)-enniatin B
(3S,6R,9S,12R,15S,18R)-3,6,9,12,15,18-Hexaisopropyl-4,10,16-trimethyl-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone
H02S2TZR95
MFCD00236425

Biological Activity

[Description]:

Fusafungine (Bioparox; Fusaloyos; Locabiotal) is a potent and orally active antibiotic and anti-inflammatory agent. Fusafungine has the potential for the research of upper respiratory airways disease (URAD)[1][2].

[Related Catalog]:

Research Areas >> Inflammation/Immunology
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Hedenmalm K, et al. Effect of withdrawal of fusafungine from the market on prescribing of antibiotics and other alternative treatments in Germany: a pharmacovigilance impact study. Eur J Clin Pharmacol. 2019 Jul;75(7):979-984.  

[2]. Akbas Y, et al. The effect of fusafungine on post-operative pain and wound healing after pediatric tonsillectomy. Int J Pediatr Otorhinolaryngol. 2004 Aug;68(8):1023-6.  

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
827.0±65.0 °C at 760 mmHg

[ Melting Point ]:
125-129°

[ Molecular Formula ]:
C33H57N3O9

[ Molecular Weight ]:
639.820

[ Flash Point ]:
454.0±34.3 °C

[ Exact Mass ]:
639.409485

[ LogP ]:
3.05

[ Vapour Pressure ]:
0.0±3.0 mmHg at 25°C

[ Index of Refraction ]:
1.460

Related Compounds