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MHY908

Names

[ CAS No. ]:
1393371-39-5

[ Name ]:
MHY908

[Synonym ]:
mhy 908

Biological Activity

[Description]:

MHY908 is a potent dual agonist of PPARα and PPARγ[1]. MHY908 also inhibits melanogenesis through inhibition of mushroom tyrosinase activity[2].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR

Research Areas >> Metabolic Disease

[References]

[1]. Park MH, et al. Potent anti-diabetic effects of MHY908, a newly synthesized PPAR α/γ dual agonist in db/db mice. PLoS One. 2013 Nov 14;8(11):e78815.

[2]. Park MH, et al. Inhibition of melanogenesis by 2-[4-(5-chlorobenzo[d]thiazol-2-yl)phenoxy]-2-methylpropanoic acid (MHY908). Arch Pharm Res. 2015 Apr;38(4):505-11.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₄ClNO₃S

[ Molecular Weight ]:
347.82

[ Exact Mass ]:
347.03800

[ PSA ]:
87.66000

[ LogP ]:
4.85870

Related Compounds