<Suppliers Price>

Fmoc-Val-Ala-PAB-PNP

Names

[ CAS No. ]:
1394238-92-6

[ Name ]:
Fmoc-Val-Ala-PAB-PNP

[Synonym ]:
MFCD28557283

Biological Activity

[Description]:

Fmoc-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[References]

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Chemical & Physical Properties

[ Density]:
1.322±0.06 g/cm3(Predicted)

[ Boiling Point ]:
931.4±65.0 °C(Predicted)

[ Molecular Formula ]:
C37H36N4O9

[ Molecular Weight ]:
680.70

Safety Information

[ Hazard Codes ]:
Xn

Related Compounds