2-hydroxy Docosanoic Acid

Names

[ CAS No. ]:
13980-14-8

[ Name ]:
2-hydroxy Docosanoic Acid

[Synonym ]:
2-Hydroxy-docosansaeure
2-HYDROXYDOCOSANOIC ACID
2-HYDROXY C22:0 ACID
dl-A-hydroxybehenic acid

Biological Activity

[Description]:

2-Hydroxydocosanoic acid has antioxidant, cholinesterase inhibitory, and antimicrobial activities[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

2-Hydroxydocosanoic acid has an IC50 of 7.6 µg/mL for DPPH[1]. 2-Hydroxydocosanoic acid shows inhibition of the AChE and BChE (IC50=68.65 µg/mL and 49.52 µg/mL, respectively) [1]. 2-Hydroxydocosanoic acid has MIC value of ≤125, ≤250, and ≤150 µg/mL for E. coli, P. aeruginosa, and S. aureus, respectively[1].

[References]

[1]. A Al-Hamoud G, et al. Abubidentin A, New Oleanane-type Triterpene Ester from Abutilon bidentatum and its antioxidant, cholinesterase and antimicrobial activities. PeerJ. 2022;10:e13040. Published 2022 Mar 8.

Chemical & Physical Properties

[ Density]:
0.928 g/cm3

[ Boiling Point ]:
484.2ºC at 760 mmHg

[ Melting Point ]:
96-97ºC

[ Molecular Formula ]:
C₂₂H₄₄O₃

[ Molecular Weight ]:
356.58300

[ Flash Point ]:
260.8ºC

[ Exact Mass ]:
356.32900

[ PSA ]:
57.53000

[ LogP ]:
6.86370

[ Vapour Pressure ]:
2.07E-11mmHg at 25°C

[ Index of Refraction ]:
1.469

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2918199090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918199090

[ Summary ]:
2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

On the isolation of 2-hydroxydocosanoic and 2-hydroxytricosanoic acids from the marine sponge Amphimedon compressa.

Lipids 24(1) , 89-91, (1989)

The first alpha-hydroxy fatty acids from a marine sponge, namely 2-hydroxydocosanoic and 2-hydroxytricosanoic, were identified in the Caribbean sponge Amphimedon compressa. These acids were found to o...