2-(Azido-PEG2-amido)-1,3-propandiol
Names
[ CAS No. ]:
1398044-52-4
[ Name ]:
2-(Azido-PEG2-amido)-1,3-propandiol
[Synonym ]:
MFCD22574770
Propanamide, 3-[2-(2-azidoethoxy)ethoxy]-N-[2-hydroxy-1-(hydroxymethyl)ethyl]-
3-[2-(2-Azidoethoxy)ethoxy]-N-(1,3-dihydroxy-2-propanyl)propanamide
Biological Activity
[Description]:
2-(Azido-PEG2-amido)-13-propandiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[Related Catalog]:
[Target]
PEGs
[In Vitro]
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C10H20N4O5
[ Molecular Weight ]:
276.290
[ Exact Mass ]:
276.143372
[ LogP ]:
-1.82