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Milameline hydrochloride

Names

[ CAS No. ]:
139886-04-7

[ Name ]:
Milameline hydrochloride

[Synonym ]:
Milameline hydrochloride (USAN)
MILAMELINE HYDROCHLORIDE
CI 979
3-Pyridinecarboxaldehyde,1,2,5,6-tetrahydro-1-methyl-,O-methyloxime,monohydrochloride,(E)
Miramelin
2-Hydroxysaclofen

Biological Activity

[Description]:

Milameline (CI 979) hydrochloride is a muscarinic receptor agonist that improves cognition[1].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> mAChR
Signaling Pathways >> GPCR/G Protein >> mAChR
Research Areas >> Neurological Disease

[References]

[1]. Schwarz RD, Callahan MJ, Coughenour LL, et al. Milameline (CI-979/RU35926): a muscarinic receptor agonist with cognition-activating properties: biochemical and in vivo characterization. J Pharmacol Exp Ther. 1999;291(2):812-822.   

Chemical & Physical Properties

[ Boiling Point ]:
221.1ºC at 760mmHg

[ Molecular Formula ]:
C8H15ClN2O

[ Molecular Weight ]:
190.67

[ Flash Point ]:
87.5ºC

[ Exact Mass ]:
190.08700

[ PSA ]:
24.83000

[ LogP ]:
1.62040

[ Vapour Pressure ]:
0.109mmHg at 25°C

Related Compounds